Indications
Montelukast Sodium is shown for: Prophylaxis and constant treatment of asthma Acute avoidance of Exercise-Induced Bronchoconstriction (EIB) Relief of side effects of Unfavorably susceptible Rhinitis (AR): Regular & Perpetual Unfavorably susceptible Rhinitis
Pharmacology
Montelukast could be a specific and orally dynamic leukotriene receptor enemy that restrains the cysteinyl leukotriene receptor (CysLT1). The cysteinyl leukotrienes (LTC4, LTD4, LTE4) are items of arachidonic corrosive digestion system and are discharged from different cells, counting pole cells and eosinophils. Cysteinyl leukotrienes and leukotriene receptor occupation have been connected with the pathophysiology of asthma & unfavorably susceptible rhinitis, counting aviation route edema, smooth muscle withdrawal, and changed cellular movement related with the fiery prepare, which contribute to the signs and indications of asthma.
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